Image of human RPA complex bound to ssDNA

Model of the human RPA complex bound to ssDNA.

All domains of RPA are shown with RPA1 in green, RPA2 in blue, RPA3 in red and ssDNA in black.  Model was developed using the known structures of the domains of RPA and the structure of Ustalago RPA bound to DNA (Fan J & Pavletich NP. 2012. Genes Dev 26:2337).  For more details about RPA-DNA interactions see Chen, R. and Wold, M.S. (2014) “Replication protein A: Single-stranded DNA's first responder: Dynamic DNA-interactions allow replication protein A to direct single-strand DNA intermediates into different pathways for synthesis or repair”Bioessays doi: 10.1002/bies.201400107.  PMID:25171654.

Chen and Wold -Bioessays

Events

Biology Seminar: "Defining Cell Type and Cell State: What did we learn from the Soybean Single-Cell Transcriptome Atlas?" promotional image

Biology Seminar: "Defining Cell Type and Cell State: What did we learn from the Soybean Single-Cell Transcriptome Atlas?"

Friday, November 14, 2025 3:30pm
Biology Building East
The Department of Biology’s seminar speaker on Friday, Nov. 14, at 3:30 p.m. is Marc Libault, a Professor in the Division of Plant Science and Technology at the University of Missouri. His seminar will be held in Kollros Auditorium (Room 101), Biology Building East (BBE). Chi-Lien Cheng is the faculty host. A reception with refreshments will be held in the BBE Lobby following the seminar.
College of Pharmacy PSET Seminar Series: Leslie Benet, PhD promotional image

College of Pharmacy PSET Seminar Series: Leslie Benet, PhD

Tuesday, November 18, 2025 11:30am
College of Pharmacy Building

The Department of Pharmaceutical Sciences and Experimental Therapeutics (PSET) in the College of Pharmacy will host a seminar presented by: 

Leslie Benet, PhD
Professor
Department of Bioengineering & Therapeutic Sciences
University of California San Francisco
San Francisco, California

All are welcome to attend. No pre-registration required.

Seminar Title: "Simplifying the Application and Teaching of Clinical Pharmacokinetics"

College of Pharmacy PSET Seminar Series: Robin Bogner, PhD

Tuesday, December 2, 2025 11:30am
College of Pharmacy Building

The Department of Pharmaceutical Sciences and Experimental Therapeutics (PSET) in the College of Pharmacy will host a seminar presented by: 

Robin Bogner, PhD
Director, Kildsig Center for Pharmaceutical Processing Research (CPPR)
Department of Pharmaceutical Sciences
University of Connecticut
Storrs, Connecticut

All are welcome to attend. No pre-registration required.