Image of human RPA complex bound to ssDNA

Model of the human RPA complex bound to ssDNA.

All domains of RPA are shown with RPA1 in green, RPA2 in blue, RPA3 in red and ssDNA in black.  Model was developed using the known structures of the domains of RPA and the structure of Ustalago RPA bound to DNA (Fan J & Pavletich NP. 2012. Genes Dev 26:2337).  For more details about RPA-DNA interactions see Chen, R. and Wold, M.S. (2014) “Replication protein A: Single-stranded DNA's first responder: Dynamic DNA-interactions allow replication protein A to direct single-strand DNA intermediates into different pathways for synthesis or repair”Bioessays doi: 10.1002/bies.201400107.  PMID:25171654.

Chen and Wold -Bioessays

Events

Biochemistry Seminar: "Repair of Stalled Replication by DNA Remodeling Enzymes" promotional image

Biochemistry Seminar: "Repair of Stalled Replication by DNA Remodeling Enzymes"

Thursday, September 17, 2026 10:30am to 11:20am
Medical Education Research Facility

"Repair of Stalled Replication by DNA Remodeling Enzymes"

Presented by

Brandt Eichman, Ph.D.
William R. Kenan, Jr. Chair
Professor of Biological Sciences
Professor of Biochemistry
Vanderbilt University

BMB Research Workshop

Tuesday, September 22, 2026 12:30pm to 1:20pm
Medical Education Research Facility

The Department of Biochemistry and Molecular Biology holds research workshops featuring internal speakers on Tuesdays, 12:30-1:20pm. For Fall 2026, these will occur in 1117 MERF. Presentation titles are not publicly available due to the use of unpublished research. Individuals interested in attending workshops or being added to the email list should contact the office at biochem@uiowa.edu.

Aug. 25: CANCELED

Sept. 1: CANCELED

Sept. 8: RESERVED

Sept. 15: Steve Guzman, PhD, Postdoc Fellow, Biomedical...

Biochemistry Seminar: "Dynamic Enzyme Assemblies Regulate Nucleotide Biosynthesis" promotional image

Biochemistry Seminar: "Dynamic Enzyme Assemblies Regulate Nucleotide Biosynthesis"

Thursday, September 24, 2026 10:30am to 11:20am
Medical Education Research Facility

"Dynamic Enzyme Assemblies Regulate Nucleotide Biosynthesis"

Presented by

Justin Kollman, Ph.D.
Earl W. Davie/ZymoGenetics Endowed Chair in Biochemistry
Professor of Biochemistry
University of Washington