Image of human RPA complex bound to ssDNA

Model of the human RPA complex bound to ssDNA.

All domains of RPA are shown with RPA1 in green, RPA2 in blue, RPA3 in red and ssDNA in black.  Model was developed using the known structures of the domains of RPA and the structure of Ustalago RPA bound to DNA (Fan J & Pavletich NP. 2012. Genes Dev 26:2337).  For more details about RPA-DNA interactions see Chen, R. and Wold, M.S. (2014) “Replication protein A: Single-stranded DNA's first responder: Dynamic DNA-interactions allow replication protein A to direct single-strand DNA intermediates into different pathways for synthesis or repair”Bioessays doi: 10.1002/bies.201400107.  PMID:25171654.

Chen and Wold -Bioessays

Events

BMB Research Workshop

Tuesday, November 3, 2026 12:30pm to 1:20pm
Medical Education Research Facility

The Department of Biochemistry and Molecular Biology holds research workshops featuring internal speakers on Tuesdays, 12:30-1:20pm. For Fall 2026, these will occur in 1117 MERF. Presentation titles are not publicly available due to the use of unpublished research. Individuals interested in attending workshops or being added to the email list should contact the office at biochem@uiowa.edu.

Aug. 25: CANCELED

Sept. 1: CANCELED

Sept. 8: RESERVED

Sept. 15: Steve Guzman, PhD, Postdoc Fellow, Biomedical...

Health Sciences Research Day 2026 promotional image

Health Sciences Research Day 2026

Thursday, November 5, 2026 12:00pm to 4:00pm
Medical Education Research Facility

The Carver College of Medicine Office of Research will celebrate and showcase the breadth of research taking place on campus at the 2026 Health Sciences Research Day. This event features keynote speaker David Clapham, MD, PhD, a poster session, and a reception. Come see what your friends and colleagues are discovering!

We encourage all researchers, faculty, staff, post-doctoral fellows, graduate students, and undergraduate students to participate in the poster session.
Abstracts must be submitted...

The 21st Harold W. Beams Lecture: Mariana Wolfner, PhD promotional image

The 21st Harold W. Beams Lecture: Mariana Wolfner, PhD

Friday, November 6, 2026 3:30pm
Biology Building East
The Department of Biology’s seminar on Friday, November 6, is the 21st Harold W. Beams Lecture featuring Mariana Wolfner, PhD, Distinguished Professor of Molecular Biology and Genetics and a Stephen H. Weiss Presidential Fellow in the Department of Molecular Biology and Genetics at Cornell University. Dr. Wolfner’s talk will be held at 3:30pm in Kollros Auditorium (Room 101), Biology Building East (BBE).